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PP7 - UNIVE - University Ca’ Foscari Venice - Dept. Of Molecular Sciences and Nanosystems

Electrochemical biosensors; electrocatalytic and bioaffinity devices.


DESCRIPTION OF ORGANIZATION/DEPARTMENT

Ca' Foscari University, established on August 6th, 1868 as a Business School (the first in Italy and the second in Europe), is a public university based in Venice. Today Ca’ Foscari University of Venice covers four large scientific and cultural areas (corresponding to the four Faculties in force until 2010): Economics, Foreign Languages and Literatures, Humanities and Sciences.
The Department of Molecular Sciences and Nanosystems combines traditional areas in the field of chemistry and integrated studies on renewable energy sources, green chemistry, nanotechnologies and biotechnologies; the Laboratory of Sensors for Electroanalysis belongs to this last research area. Indeed, the group has developed original know-how in the field of the fabrication and analytical application of ensembles and arrays of nanoelectrodes, nanostructured electroactive membranes and polymer-based electrodes.
 


TECHNOLOGIES AND EXPERTISE AVAILABLE

Analytical and electroanalytical techniques; fabrication, modification and characterization of electrochemical sensors; study of electroactive molecules particularly interesting in environmental and bio-medical fields.
 


FIELD OF RESEARCH/ACTIVITIES

The research activity of the group focuses on the study and development of analytical sensors and devices, which can be used also outside the walls of a specialized chemical laboratory, i.e. for decentralized and in field analyses. To this goal, the most recent advancements in the field of nanotechnology are applied; this allowed the achievement of dramatic improvements as far as miniaturization, functionalization of surfaces and analytical performances are involved. The results of these researches are applied mainly in the environmental and bio-medical field.
Within T2C Project, the group has started two different collaborations, with the common goal to develop bioelectrochemical sensors for clinical/molecular diagnostics. In collaboration with the Dept. of Life Sciences of the University of Trieste, it is developing nanostructured sensing devices for the detection of the bile pigment bilirubin, a major plasma biomarker of hemolysis, hepatic function and cardiovascular risk. In collaboration with the Institute of Child Health IRCCS Burlo Garofolo of Trieste, it is developing novel electrochemical sensors for the detection of autoantibodies involved in coeliac disease, a widespread condition characterized by an inflammatory intestinal disease associated with malabsorption.
 


KEY WORDS

Electrochemistry, sensors, biosensing, analytical chemistry, nanotechnology